Diabetes Medication Protocol
For Procedures Requiring IV Sedation
Oral Medications (pills or tablets):
• Hold all oral or non-insulin injectable diabetes medications the morning of the procedure.
Insulin Therapy:
1. Type 1 Diabetes:
o Reduce basal insulin (NPH, glargine, Detemir) by 50% on the evening before procedure.
o Hold all other insulin on the day of the procedure.
2. Type 2 Diabetes:
o NPH and Lente:
If your procedure/surgery is before 12 PM, reduce the evening dose before your procedure/surgery by 20% and reduce dose on the morning of the procedure/surgery by 50%.
If your procedure/surgery is after 12 PM, reduce the dose by 50% on the morning of the procedure/surgery.
o Glargine (U100, U300), Detemir, Degludec (U100, U200)
If you take this in the mornings, reduce by 50% on the morning of the procedure/surgery.
If you take this in the evening, reduce by 50% the dose on the evening before the procedure/surgery.
o Split-Mixed Insulin (70/30, 75/25, 50/50)
Reduce evening dose prior to procedure by 20%, and reduce morning of the procedure dose by 50%.
o Pump Basal Insulin
Continue basal rate ONLY on the day of procedure.
Stop all other insulin.